Ways to interact:

https://developer.chrome.com/docs/extensions/reference/accessibilityFeatures/

https://developer.chrome.com/docs/extensions/reference/contextMenus/

https://developer.chrome.com/docs/extensions/reference/declarativeContent/

https://developer.chrome.com/docs/extensions/reference/declarativeNetRequest/

https://developer.chrome.com/docs/extensions/reference/dom/

https://developer.chrome.com/docs/extensions/reference/tabCapture/

https://developer.chrome.com/docs/extensions/reference/i18n/

we can walk the tree:

https://developer.mozilla.org/en-US/docs/Web/API/Element/children

https://developer.mozilla.org/en-US/docs/Web/API/MutationObserver

https://developer.mozilla.org/en-US/docs/Web/API/TreeWalker

Sites

1. Youtube
2. Fox news
3. New York Times
4. The Blaze
5. Google